The Ultimate Boost: 13 Benefits of Liposomal Glutathione

Written by Angie Arriesgado
featured image for blog on 13 liposomal glutathione benefits

Do you know what toxic chemicals, pollutants, preservatives, cigarette smoke, and ultraviolet light have in common? They all increase free radicals in our bodies! Thankfully, antioxidants like our Liposomal Glutathione combat these harmful molecules. Scroll down to discover the top 13 benefits of liposomal glutathione that everyone should know!

13 Amazing Liposomal Glutathione Benefits

1.   Better bioavailability compared to oral glutathione

If you’re considering glutathione (GSH) supplements, liposomal GSH is the best choice. Why? Because ordinary oral GSH supplements are poorly absorbed by the body. 1 When you take a regular GSH pill, it gets broken down in your stomach and isn’t fully absorbed.

liposomal glutathione and vitamin c

On the other hand, liposomal glutathione has superior bioavailability due to liposome technology. 2 This technology involves inserting glutathione into tiny vesicles called liposomes, which are covered in phosphatidylcholine.

Since phosphatidylcholine is naturally found in the body, it isn’t seen as a threat, allowing for better absorption. This makes liposomal glutathione much more effective than regular oral GSH supplements.

To ensure you get the best protection, we’ve combined glutathione with another potent antioxidant, Vitamin C. Meet our Liposomal Glutathione & Vitamin C supplement! Each serving (10 ml or 2 tsp) provides 500 mg of reduced L-Glutathione in liposomes and 1,000 mg of Vitamin C, creating a powerful antioxidant duo to combat oxidative stress.

2.   Fights oxidative stress by neutralizing free radicals

Free radicals are natural byproducts of metabolism and pollutants. While our body uses glutathione to eliminate them, an excess leads to oxidative stress, damaging DNA, cells, and proteins. Eventually, this leads to health issues.

You can replenish your antioxidant supply by eating veggies and fruits. However, not everybody lives a healthy lifestyle and eats a balanced diet. So, supplementing with glutathione is the best option to help your body fight oxidative stress.

3.   Liposomal glutathione also reduces inflammation

Oxidative stress can lead to inflammation. When there’s not enough antioxidants in the body, the inflammation can become chronic. This can lead to the development of disease.

Signs of chronic inflammation include fatigue, body pains, mood disorders, and frequent infections.

Fortunately, glutathione can treat inflammation by fighting oxidative stress. In one study, glutathione was able to treat lung disease brought about by inflammation. 3

4.   May improve insulin sensitivity

People with insulin resistance have low glutathione levels. 4 Since insulin resistance increases the risk of type 2 diabetes and cardiovascular diseases, consider supplementing with GSH. Fortunately, this is one of many liposomal glutathione benefits – GSH has been shown to help improve insulin sensitivity!

5.   Regenerates other antioxidants like vitamins C and E

This is one of glutathione’s most notable properties. As the body’s master antioxidant, GSH is capable of regenerating other antioxidants – like Vitamins C and E – to help win its fight against free radicals. 5

6.   Master detoxifier in action!

Our body’s main detoxifier is the liver. Guess what’s found in huge quantities there? If you guessed glutathione, you’re right! GSH can protect us against toxic materials and pollutants.

So, how it works is that GSH molecules bind to these pollutants, e.g. alcohol, heavy metals, toxins, etc., and transform them into water-soluble compounds. This conversion allows the pollutants to exit the body without causing further harm.

For heavy metal poisoning, intravenous glutathione is the best treatment option as it ensures maximum absorption. 6

one of liposomal glutathione's benefits is you'll have more energy

7.   Have more energy throughout the day

GSH protects the mitochondria (our cell’s powerhouse) from free radicals and oxidative damage. This allows the mitochondria to go on producing more energy for our cells. So, if you’ve been feeling sluggish lately, try taking liposomal glutathione!

8.    Uplifts your mood

Low glutathione levels can lead to mood disorders like excessive anxiety and depression. Fortunately, research suggests that by simply re-upping your body’s glutathione stores (either through food or supplements), these symptoms may be reversed and managed. 7

9.  May improve brain health

GSH doesn’t just work on mood disorders, it may also help improve brain health. People with schizophrenia, bipolar disorder, and obsessive-compulsive disorder often have low GSH levels in the brain. The good news is that supplementing with liposomal glutathione may help make these conditions much more manageable. 8 9 10

10.  Glutathione may help boost your immune function

With all the liposomal glutathione benefits we’ve discussed so far, it’s natural to assume that GSH can also boost your immunity. But is this really the case?

When left uncontrolled, free radicals can do a lot of damage to our health. But by neutralizing them, you’re protecting your body from succumbing to these health problems. 11

With healthy GSH levels in your body, your immune system isn’t spread out so thinly. It can work more effectively at dealing with “intruders” as they come in contact with your body! This means you spend less time getting sick and more time enjoying life!

taking glutathione can lead to lighter and younger looking skin

11.  Lighter and younger-looking skin

Surprised? This is one of the more interesting side effects of taking glutathione supplements.

According to a 2017 study, Thai women taking glutathione have noticed improved skin elasticity, fewer wrinkles, and lighter complexion. 12 A separate study done on Filipino women also showed the same results. 90% of the volunteers experienced less melanin pigmentation, which ultimately led to skin lightening. 13

12.  Glutathione may help with non-alcoholic fatty liver disease (NAFLD)  

Some studies suggest that supplementing with GSH might help with NAFLD, a liver disease that damages liver cells and lowers GSH levels.

For instance, one study showed that taking 300 mg/day of oral GSH might prevent NAFLD from worsening to non-alcoholic steatohepatitis (NASH). 14 Additionally, another study found that patients who took 300 mg/day of oral GSH for 4 months showed reduced liver fat and damage markers, indicating potential benefits for NAFLD patients. 15

13. Glutathione may help keep your eyes healthy

Glutathione (GSH) is a vital antioxidant in the eye, protecting the retina and macula from harmful molecules that can cause damage. This protection is crucial in preventing age-related macular degeneration (AMD), a common eye disease in older adults that can lead to vision loss.

Maintaining adequate GSH levels through diet or supplements may help protect vision and prevent degenerative eye conditions. 16

Conclusion

These Liposomal Glutathione benefits are nothing to scoff at – and this is just the tip of the iceberg! As more studies are done on glutathione, we may discover even more benefits to supplementing with nature’s master antioxidant.


References:

  1. Allen, Jason, and Ryan D. Bradley. “Effects of Oral Glutathione Supplementation on Systemic Oxidative Stress Biomarkers in Human Volunteers.” The Journal of Alternative and Complementary Medicine, vol. 17, no. 9, Sept. 2011, pp. 827–833, https://doi.org/10.1089/acm.2010.0716. ‌ ↩︎
  2. Sinha, R., et al. “Oral Supplementation with Liposomal Glutathione Elevates Body Stores of Glutathione and Markers of Immune Function.” European Journal of Clinical Nutrition, vol. 72, no. 1, 1 Jan. 2018, pp. 105–111, https://doi.org/10.1038/ejcn.2017.132.‌ ↩︎
  3. Ghezzi, P. “Role of Glutathione in Immunity and Inflammation in the Lung.” International Journal of General Medicine, Jan. 2011, p. 105, https://doi.org/10.2147/ijgm.s15618. ↩︎
  4. Lutchmansingh, Fallon K., et al. “Glutathione Metabolism in Type 2 Diabetes and Its Relationship with Microvascular Complications and Glycemia.” PLOS ONE, vol. 13, no. 6, 7 June 2018, p. e0198626, https://doi.org/10.1371/journal.pone.0198626. ‌ ↩︎
  5. Pizzorno, Joseph. “Glutathione!” Integrative Medicine (Encinitas, Calif.), vol. 13, no. 1, 1 Feb. 2014, pp. 8–12, pubmed.ncbi.nlm.nih.gov/26770075/. ‌ ↩︎
  6. Honda, Yasushi, et al. “Efficacy of Glutathione for the Treatment of Nonalcoholic Fatty Liver Disease: An Open-Label, Single-Arm, Multicenter, Pilot Study.” BMC Gastroenterology, vol. 17, 8 Aug. 2017, https://doi.org/10.1186/s12876-017-0652-3. ‌ ↩︎
  7. Krolow, R., et al. “Oxidative Imbalance and Anxiety Disorders.” Current Neuropharmacology, vol. 12, no. 2, 31 Mar. 2014, pp. 193–204, https://doi.org/10.2174/1570159×11666131120223530. ↩︎
  8. Sonthalia, Sidharth, et al. “Glutathione as a Skin Whitening Agent: Facts, Myths, Evidence and Controversies.” Indian Journal of Dermatology, Venereology, and Leprology, vol. 82, no. 3, 2016, p. 262, https://doi.org/10.4103/0378-6323.179088. ‌ ↩︎
  9. Berk, Michael, et al. “N-Acetyl Cysteine as a Glutathione Precursor for Schizophrenia—a Double-Blind, Randomized, Placebo-Controlled Trial.” Biological Psychiatry, vol. 64, no. 5, Sept. 2008, pp. 361–368, https://doi.org/10.1016/j.biopsych.2008.03.004. ↩︎
  10. Cui, J., et al. “Role of Glutathione in Neuroprotective Effects of Mood Stabilizing Drugs Lithium and Valproate.” Neuroscience, vol. 144, no. 4, 23 Feb. 2007, pp. 1447–1453, https://doi.org/10.1016/j.neuroscience.2006.11.010. ‌ ↩︎
  11. Ballatori, Nazzareno, et al. “Glutathione Dysregulation and the Etiology and Progression of Human Diseases.” Biological Chemistry, vol. 390, no. 3, 1 Mar. 2009, pp. 191–214, https://doi.org/10.1515/BC.2009.033. ‌ ↩︎
  12. Weschawalit, Sinee, et al. “Glutathione and Its Antiaging and Antimelanogenic Effects.” Clinical, Cosmetic and Investigational Dermatology, vol. Volume 10, Apr. 2017, pp. 147–153, https://doi.org/10.2147/ccid.s128339. ↩︎
  13. Handog, Evangeline B., et al. “An Open-Label, Single-Arm Trial of the Safety and Efficacy of a Novel Preparation of Glutathione as a Skin-Lightening Agent in Filipino Women.” International Journal of Dermatology, vol. 55, no. 2, 3 July 2015, pp. 153–157, https://doi.org/10.1111/ijd.12999.‌ ↩︎
  14. Irie, Makoto, et al. “Reduced Glutathione Suppresses Oxidative Stress in Nonalcoholic Fatty Liver Disease.” Euroasian Journal of Hepato-Gastroenterology, vol. 6, no. 1, 2016, pp. 13–18, https://doi.org/10.5005/jp-journals-10018-1159. ↩︎
  15. Honda, Yasushi, et al. “Efficacy of Glutathione for the Treatment of Nonalcoholic Fatty Liver Disease: An Open-Label, Single-Arm, Multicenter, Pilot Study.” BMC Gastroenterology, vol. 17, 8 Aug. 2017, https://doi.org/10.1186/s12876-017-0652-3. ‌ ↩︎
  16. Sylwia Brodzka, et al. “The Role of Glutathione in Age-Related Macular Degeneration (AMD).” International Journal of Molecular Sciences, vol. 25, no. 8, 9 Apr. 2024, pp. 4158–4158, https://doi.org/10.3390/ijms25084158.‌ ↩︎

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