Glow Naturally With Liposomal Glutathione’s Skin Benefits

Looking for a natural way to achieve radiant, clear skin without breaking the bank on treatments? Glutathione might be your answer. In this post, we’ll dive into how it helps with skin aging, brightening, acne, and hyperpigmentation—and why our Liposomal Glutathione + Vitamin C is the best option for maximizing these benefits.

Can Glutathione help with skin aging?

Absolutely. Glutathione plays a key role in slowing down skin aging by tackling oxidative stress – one of the main causes of wrinkles, fine lines, and loss of skin elasticity. Oxidative stress happens when there’s an imbalance between free radicals and antioxidants, leading to faster aging. ¹

As the body’s master antioxidant, glutathione neutralizes free radicals, helping preserve the skin’s firmness and elasticity. It also shields the skin from external aging factors like UV radiation, making it a powerful anti-aging skincare ingredient. ²

Can Glutathione help improve skin tone?

Yes, glutathione is an excellent natural option for achieving a more even complexion without resorting to harsh chemicals. It works by interfering with melanin production, the pigment responsible for skin color. 

Glutathione blocks the interaction between tyrosinase and L-DOPA – two substances needed for melanin production. Even if melanin production has already started, glutathione prevents the melanin from clumping together. This dual action reduces melanin levels and results in a lighter, more uniform complexion. ³

Research also shows that glutathione, even at lower doses of 250 mg/day, can effectively reduce melanin in both its reduced (GSH) and oxidized (GSSG) forms, making it a popular ingredient in skin-lightening treatments to improve skin tone. ⁴

Can Glutathione reduce hyperpigmentation?

Yes, glutathione may help reduce hyperpigmentation, a condition that causes dark spots and uneven skin tone. While hyperpigmentation isn’t typically itchy or painful, it can impact self-confidence. 

In a study on women with melasma (a type of hyperpigmentation caused by hormonal changes and sun exposure), higher glutathione levels were linked to milder cases. This suggests that glutathione may help protect against the progression of this condition. ^{5 6}

Another study of Thai medical students who took 250 mg of glutathione twice daily for four weeks found reduced melanin levels and noticeable improvements in dark spots. ⁷

Similarly, a study involving 30 Filipino women with darker skin tones reported significant melanin reduction as early as two weeks. By the end of the eight-week trial, participants experienced substantial skin lightening and improved appearance of dark spots. ⁸

Overall, glutathione’s dual ability to reduce melanin production and shift synthesis from darker eumelanin to lighter pheomelanin makes it a promising solution for various forms of hyperpigmentation. ⁹

Can Glutathione help with acne?  

Yes, research suggests that glutathione may help tackle one of the root causes of acne – oxidative stress. ¹⁰

Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body, which can damage skin cells and lead to inflammation. This inflammation, in turn, contributes to the formation of acne. ¹¹

In a small study, participants with mild to moderate acne who took 500 mg of oral glutathione daily for 4 weeks saw a reduction in acne severity and improved skin condition, with no major side effects. While promising, more research is needed to confirm these results. ¹²

Why choose Liposomal Glutathione + Vitamin C for skin health?

Now that we’ve explored how glutathione benefits your skin, let’s look at why our Liposomal Glutathione + Vitamin C formula is the best choice to maximize those benefits.

Added Benefits of Vitamin C

Our formula also includes Vitamin C, a powerful antioxidant that boosts collagen production, keeping skin firm and youthful while reducing wrinkles. ¹³ Vitamin C works together with glutathione to regenerate it, prolonging its activity and further protecting your skin from oxidative stress and environmental damage. ¹⁴

Enhanced Absorption with Liposomal Technology

Traditional glutathione supplements are often poorly absorbed because digestive enzymes break them down before reaching the bloodstream. ¹⁵ To solve this, we use liposomal technology. 

Liposomes are tiny fat-based vesicles that protect glutathione as it passes through the digestive system, allowing for better absorption. Made from phosphatidylcholine (a natural component of cell membranes), these liposomes ensure more glutathione reaches your bloodstream, thus effectively enhancing skin health. ^{16 17}

How much Liposomal Glutathione should you take to enjoy healthy skin?

The standard serving of our Liposomal Glutathione + Vitamin C is 10 ml (about two teaspoons), providing 500 mg of Liposomal Glutathione and 1,000 mg of Vitamin C.

If you’re new to glutathione, it’s best to start slow. Begin with 2.5 ml (half a teaspoon) to allow your body to adjust, as starting too fast may trigger the body’s detox process, especially for those with lower glutathione levels. This detox may remove accumulated toxins, like heavy metals, from your cells.

To avoid discomfort, gradually increase the dosage over several days. If you experience any issues, reduce the dose back to 2.5 ml until your body adjusts.

Note: Always consult your doctor before starting new liposomal glutathione supplements to determine the right dosage for your specific needs.

How long should you supplement with Liposomal Glutathione?

Glutathione is naturally produced by the body, so you can safely use it as long as you want to enjoy its health benefits. Long-term supplementation at the recommended dose is generally safe, with studies showing no significant side effects.

If you decide to stop, reduce your dosage gradually by 2.5 ml every 3 to 4 days, as supplementation can reduce the body’s natural glutathione production. You can also increase glutathione levels naturally through foods rich in sulfur, like broccoli, cauliflower, spinach, garlic, green peppers, and avocados. ¹⁸

Conclusion

Our Liposomal Glutathione & Vitamin C can be a powerful supplement for those looking to achieve optimal skin health (and glow naturally as a result)! Its potent antioxidant properties, coupled with its ability to combat oxidative stress, genuinely make it a valuable addition to your skincare routine.

References:

1. Silva, Silas Arandas Monteiro E et al. “An overview about oxidation in clinical practice of skin aging.” Anais brasileiros de dermatologia vol. 92,3 (2017): 367-374. doi:10.1590/abd1806-4841.20175481 ↩︎
2. Poljšak, Borut, and Raja Dahmane. “Free Radicals and Extrinsic Skin Aging.” Dermatology Research and Practice, vol. 2012, 2012, pp. 1–4, https://doi.org/10.1155/2012/135206. ‌ ↩︎
3. MATSUKI, Mitsuo, et al. “Inhibitory Mechanism of Melanin Synthesis by Glutathione.” YAKUGAKU ZASSHI, vol. 128, no. 8, 2008, pp. 1203–1207, https://doi.org/10.1248/yakushi.128.1203. ↩︎
4. Weschawalit, Sinee, et al. “Glutathione and Its Antiaging and Antimelanogenic Effects.” Clinical, Cosmetic and Investigational Dermatology, 27 Apr. 2017, www.dovepress.com/glutathione-and-its-antiaging-and-antimelanogenic-effects-peer-reviewed-fulltext-article-CCID. ↩︎
5. Cassiano, Daniel P., et al. “Update on Melasma—Part II: Treatment.” Dermatology and Therapy, vol. 12, no. 9, 29 July 2022, pp. 1989–2012, https://doi.org/10.1007/s13555-022-00780-4. ↩︎
6. Wiraguna, Anak Agung Gde Putra, et al. “Correlation between Glutathione Plasma with Degree Severity of Melasma in Balinese Women.” Clinical, Cosmetic and Investigational Dermatology, vol. Volume 13, July 2020, pp. 455–459, https://doi.org/10.2147/ccid.s258834 ‌ ↩︎
7. Arjinpathana, Nutthavuth, and Pravit Asawanonda. “Glutathione as an Oral Whitening Agent: A Randomized, Double-Blind, Placebo-Controlled Study.” The Journal of Dermatological Treatment, vol. 23, no. 2, 1 Apr. 2012, pp. 97–102, https://doi.org/10.3109/09546631003801619. ↩︎
8. Handog, Evangeline B., et al. “An Open-Label, Single-Arm Trial of the Safety and Efficacy of a Novel Preparation of Glutathione as a Skin-Lightening Agent in Filipino Women.” International Journal of Dermatology, vol. 55, no. 2, 3 July 2015, pp. 153–157, https://doi.org/10.1111/ijd.12999.  ↩︎
9. Sonthalia, Sidharth, et al. “Glutathione as a Skin Whitening Agent: Facts, Myths, Evidence and Controversies.” Indian Journal of Dermatology, Venereology, and Leprology, vol. 82, no. 3, 2016, p. 262, https://doi.org/10.4103/0378-6323.179088 ↩︎
10. Alexa Florina Bungău, et al. “Oxidative Stress and Metabolic Syndrome in Acne Vulgaris: Pathogenetic Connections and Potential Role of Dietary Supplements and Phytochemicals.” Biomedicine & Pharmacotherapy, vol. 164, 1 Aug. 2023, pp. 115003–115003, https://doi.org/10.1016/j.biopha.2023.115003. ↩︎
11. Sarici, G, et al. “Oxidative Stress in Acne Vulgaris.” Journal of the European Academy of Dermatology and Venereology, vol. 24, no. 7, 23 Nov. 2009, pp. 763–767, https://doi.org/10.1111/j.1468-3083.2009.03505.x. ↩︎
12. Ferra, Olivia, et al. ORAL GLUTATHIONE MONOTHERAPY in MILD to MODERATE ACNE VULGARIS. Vol. 45, no. 01, 2022, www.teikyomedicaljournal.com/volume/TMJ/45/01/oral-glutathione-monotherapy-in-mild-to-moderate-acne-vulgaris-6219acf3ab371.pdf.‌ ↩︎
13. Pullar, Juliet M., et al. “The Roles of Vitamin c in Skin Health.” Nutrients, vol. 9, no. 8, 12 Aug. 2017, p. 866, www.ncbi.nlm.nih.gov/pmc/articles/PMC5579659/. ↩︎
14. Johnston, C S, et al. “Vitamin c Elevates Red Blood Cell Glutathione in Healthy Adults.” The American Journal of Clinical Nutrition, vol. 58, no. 1, 1 July 1993, pp. 103–105, academic.oup.com/ajcn/article-abstract/58/1/103/4715823?redirectedFrom=fulltext, https://doi.org/10.1093/ajcn/58.1.103. ↩︎
15. Allen, Jason, and Ryan D. Bradley. “Effects of Oral Glutathione Supplementation on Systemic Oxidative Stress Biomarkers in Human Volunteers.” The Journal of Alternative and Complementary Medicine, vol. 17, no. 9, Sept. 2011, pp. 827–833, www.ncbi.nlm.nih.gov/pmc/articles/PMC3162377 ↩︎
16. Sinha, R., et al. “Oral Supplementation with Liposomal Glutathione Elevates Body Stores of Glutathione and Markers of Immune Function.” European Journal of Clinical Nutrition, vol. 72, no. 1, 1 Jan. 2018, pp. 105–111, www.nature.com/articles/ejcn2017132, https://doi.org/10.1038/ejcn.2017.132.‌ ↩︎
17. Akbarzadeh, Abolfazl, et al. “Liposome: Classification, Preparation, and Applications.” Nanoscale Research Letters, vol. 8, no. 1, 22 Feb. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3599573 ↩︎
18. Al-Temimi, Anfal Alwan, et al. “Glutathione for Food and Health Applications with Emphasis on Extraction, Identification, and Quantification Methods: A Review.” Metabolites, vol. 13, no. 4, 24 Mar. 2023, p. 465, https://doi.org/10.3390/metabo13040465. ↩︎

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